胡方

姓名：胡方

职称：教授

联系邮箱：hufang19@smu.edu.cn

学习经历：

2006.09-2010.07 武汉大学，化学基地班，学士

2010.09-2015.07 中国科学院化学研究所，有机化学，硕博

2012.09-2015.07 北京大学，有机化学，博士

工作经历：

2015.08-2019.08 新加坡国立大学，博士后研究员

2019.09-至今 南方医科大学生物医学工程学院，教授

研究方向：

1.有机多功能生物材料

2.光动力治疗

3.肿瘤成像治疗，细菌标记杀伤

主要获奖情况：

1、海外高层次人才青年项目，2021年

2、中国分析测试协会科学技术奖二等奖，2016年

3、日本振兴学术会JSPS HOPE Fellow，2015年

主要科研课题：

1、海外高层次人才青年项目，2021-2024，主持。

2、国自然面上项目，基于聚合反应的生物正交靶向策略及其对诊疗试剂的富集作用，22077060，2021-2024，主持。

3、粤穗区域联合基金-青年基金项目，光敏剂引起的原位免疫激活对迁移性肺癌的免疫治疗，2020-2023，主持。

4、南方医科大学高层次人才项目，2019-2023，主持。

代表性论文：

(1) Hu, F.; Qi, G.; Kenry, K.; Mao, D.; Zhou, S.; Wu, M.; Wu, W.; Liu, B. Visualization and in‐situ ablation of intracellular bacterial pathogen through metabolic labeling. Angewandte Chemie International Edition 2019, 10.1002/anie.201910187. IF=12.257

(2) Qi, G.+; Hu, F.+; Kenry, K.; Shi, L.; Wu, M.; Liu, B. AIEgen‐Peptide Conjugate: Phototheranostics for Phagosome‐Entrapped Bacteria. Angewandte Chemie International Edition 2019, 10.1002/anie.201906099. IF=12.257

(3) Hu, F.; Manghnani, P.; Kenry; Feng, G.; Wu, W.; Teh, C.; Liu, B. Visualize Embryogenesis and Cell Fate Using Fluorescent Probes with Aggregation-Induced Emission. ACS applied materials & interfaces 2019, 11 (4), 3737-3744. IF= 8.456

(4) Hu, F.; Xu, S.; Liu, B. Photosensitizers with Aggregation-induced Emission: Materials and Biomedical Applications. Advanced Materials 2018, 1801350. IF=25.809

(5) Hu, F.; Mao, D.; Kenry; Cai, X.; Wu, W.; Kong, D.; Liu, B. Light-up Probe with Aggregation-Induced Emission for Real-Time Bio-orthogonal Tumor Labeling and Image-guided Photodynamic Therapy. Angewandte Chemie International Edition 2018, 57 (32), 10182-10186. IF=12.257

(6) Mao, D.+; Hu, F.+; Kenry; Ji, S.; Wu, W.; Ding, D.; Kong, D.; Liu, B. Metal-organic framework-assisted in vivo bacterial metabolic labeling and precise antibacterial therapy. Advanced Materials 2018, 1706831. IF=25.809, ESI高被引，ESI热点

(7) Hu, F.; Mao, D.; Kenry; Wang, Y.; Wu, W.; Zhao, D.; Kong, D.; Liu, B. Metal-organic framework as a simple and general inert nanocarrier for photosensitizers to implement activatable photodynamic therapy. Advanced Functional Materials 2018, 1707519. IF=15.621

(8) Hu, F.; Yuan, Y.; Wu, W.; Mao, D.; Liu, B. Dual-responsive Metabolic Precursor and Light-up AIEgen for Cancer Cell Bioorthogonal Labelling and Precise Ablation. Analytical chemistry 2018, 90 (11), 6718-6724. IF=6.35

(9) Hu, F.; Cai, X.; Manghnani, P. N.; Kenry, K.; Wu, W.; Liu, B. Multicolor Monitoring of Cellular Organelles by Single Wavelength Excitation to Visualize Mitophagy Process. Chemical Science 2018, 9, 2756-2761. IF=9.556

(10) Hu, F.; Yuan, Y.; Mao, D.; Wu, W.; Liu, B. Smart activatable and traceable dual-prodrug for image-guided combination photodynamic and chemo-therapy. Biomaterials 2017, 144, 53-59. IF=10.273

(11) Gui, B.; Yu, N.; Meng, Y.; Hu, F.*; Wang, C. Immobilization of AIEgens into metal‐organic frameworks: Ligand design, emission behavior, and applications. Journal of Polymer Science Part A: Polymer Chemistry 2017, 1809-1817. IF=2.591

(12) Hu, F.; Liu, B. Organelle-specific bioprobes based on fluorogens with aggregation-induced emission (AIE) characteristics. Organic & Biomolecular Chemistry 2016, 14, 9931-9944. IF=3.49

(13) Hu, F.; Zhang, G. X.; Zhan, C.; Zhang, W.; Yan, Y. L.; Zhao, Y. S.; Fu, H. B.; Zhang, D. Q. Highly Solid-State Emissive Pyridinium-Substituted Tetraphenylethylene Salts: Emission Color-Tuning with Counter Anions and Application for Optical Waveguides. Small 2015, 11, 1335-1344. IF=10.856

(14) Hu, F.; Huang, Y. Y.; Zhang, G. X.; Zhao, R.; Yang, H.; Zhang, D. Q. Targeted Bioimaging and Photodynamic Therapy of Cancer Cells with an Activatable Red Fluorescent Bioprobe. Analytical Chemistry 2014, 86, 7987-7995. IF=6.35, ESI高被引

(15) Huang, Y. Y.+; Hu, F.+; Zhao, R.; Zhang, G. X.; Yang, H.; Zhang, D. Q. Tetraphenylethylene Conjugated with a Specific Peptide as a Fluorescence Turn-On Bioprobe for the Highly Specific Detection and Tracing of Tumor Markers in Live Cancer Cells. Chemistry-a European Journal 2014, 20, 158-164. IF=5.16

(16) Hu, F.; Huang, Y. Y.; Zhang, G. X.; Zhao, R.; Zhang, D. Q. A highly selective fluorescence turn-on detection of hydrogen peroxide and D-glucose based on the aggregation/deaggregation of a modified tetraphenylethylene. Tetrahedron Letters 2014, 55, 1471-1474. IF=2.259